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Using two separate drugs to shed weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err to the side of caution and allow FDA do its job and demand some research be done so that the public is aware of the side effects and hazards of the medications before we take them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on their medications. Researchers found that participants investing in this drug for the year, lost weight within four weeks and have kept the extra weight off through the entire 56 weeks of the study. Contrave is a combination with the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of several active ingredient, which can make them more effective and safer. Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular is the fact that at the time of right now there are no long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise blood pressure levels and heartbeat, and must not be used in people who have a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients for the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. 
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